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TRIM45

GENERAL INFORMATION

Gene name

 TRIM45

Gene description

 Tripartite motif containing 45

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA030266
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 TRIM45 (HGNC Symbol)

Synonyms

 FLJ13181, RNF99

Description

 Tripartite motif containing 45 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]

Chromosome

 1

Cytoband

 p13.1

Chromosome location (bp)

 117111060 - 117122587

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000134253 (version 83.38)

Entrez gene

 80263

UniProt

 Q9H8W5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H8W5

Antibodypedia

 TRIM45 antibodies

PROTEIN BROWSER
TRIM45-001
TRIM45-002
TRIM45-003
TRIM45-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM45-001
ENSP00000256649
ENST00000256649
Q9H8W5 [Direct mapping]
Tripartite motif-containing protein 45
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0045171 [intercellular bridge]
GO:0046872 [metal ion binding]
GO:0060348 [bone development]
Show all
 580 aa
64.4 kDa 		No 0
TRIM45-002
ENSP00000358476
ENST00000369464
Q9H8W5 [Direct mapping]
Tripartite motif-containing protein 45
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0045171 [intercellular bridge]
GO:0046872 [metal ion binding]
Show all
 562 aa
62.5 kDa 		No 0
TRIM45-003
ENSP00000358473
ENST00000369461
Q5T2K3 [Direct mapping]
Tripartite motif-containing protein 45
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
Show all
 523 aa
58.2 kDa 		No 0
TRIM45-004
ENSP00000474935
ENST00000485032
S4R407 [Direct mapping]
Tripartite motif-containing protein 45
Show all
Predicted intracellular proteins
Show all
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
Show all
 303 aa
34.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.