Cell atlas - GOLM1 - The Human Protein Atlas

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GOLM1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus

Human cell
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	GOLM1
Gene description	Golgi membrane protein 1
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA010638 , HPA011929
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ASSAYS

RNA expression

Human cells

Custom data

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus.

Main location

Golgi apparatus (validated)


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Antibody	Cell line	Location
HPA010638	A-431	Golgi apparatus
HPA010638	U-2 OS	Golgi apparatus
HPA010638	U-251 MG	Golgi apparatus
HPA011929	A-431	Golgi apparatus
HPA011929	U-2 OS	Golgi apparatus
HPA011929	U-251 MG	Golgi apparatus

CUSTOM DATA


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Thumbnail	Antibody	Cell line	Assay	Description
	HPA010638	U-2 OS	Image	Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) for a refined protein localization within the Golgi apparatus in U-2 OS cells. GOLM1 localizes to the Golgi apparatus, but not to the cis-Golgi compartment.

GENE INFORMATION
Gene name	GOLM1 (HGNC Symbol)
Synonyms	bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73
Description	Golgi membrane protein 1 (HGNC Symbol)
Entrez gene summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Sep 2009]
Chromosome	9
Cytoband	q21.33
Chromosome location (bp)	86026146 - 86100173
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135052 (version 83.38)
Entrez gene	51280
UniProt	Q8NBJ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NBJ4
Antibodypedia	GOLM1 antibodies

PROTEIN BROWSER

GOLM1-001	GOLM1-002	GOLM1-005	GOLM1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GOLM1-001 ENSP00000373364 ENST00000388712	Q8NBJ4 [Direct mapping] Golgi membrane protein 1 B3KNK9 [Target identity:100%; Query identity:100%] Epididymis luminal protein 46; Golgi phosphoprotein 2, isoform CRA_a; cDNA FLJ14811 fis, clone NT2RP4001975, highly similar to Golgi phosphoprotein 2; cDNA PSEC0257 fis, clone NT2RP3003642, highly similar to golgi phosphoprotein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005794 [Golgi apparatus] GO:0005887 [integral component of plasma membrane] GO:0006997 [nucleus organization] GO:0019216 [regulation of lipid metabolic process] GO:0070062 [extracellular exosome] Show all	401 aa 45.3 kDa	Yes	0
GOLM1-002 ENSP00000373363 ENST00000388711	Q8NBJ4 [Direct mapping] Golgi membrane protein 1 B3KNK9 [Target identity:100%; Query identity:100%] Epididymis luminal protein 46; Golgi phosphoprotein 2, isoform CRA_a; cDNA FLJ14811 fis, clone NT2RP4001975, highly similar to Golgi phosphoprotein 2; cDNA PSEC0257 fis, clone NT2RP3003642, highly similar to golgi phosphoprotein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005794 [Golgi apparatus] GO:0005887 [integral component of plasma membrane] GO:0070062 [extracellular exosome] Show all	401 aa 45.3 kDa	Yes	0
GOLM1-005 ENSP00000418155 ENST00000466178	C9J941 [Direct mapping] Golgi membrane protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		80 aa 9 kDa	Yes	0
GOLM1-006 ENSP00000419076 ENST00000486130	C9JYM4 [Direct mapping] Golgi membrane protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		121 aa 13.7 kDa	Yes	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.