Cell atlas - GPR55 - The Human Protein Atlas

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GPR55

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GPR55
Gene description	G protein-coupled receptor 55
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (Karpas-707, HDLM-2, SK-MEL-30)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Karpas-707, HDLM-2, SK-MEL-30) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GPR55
Synonyms
Description	G protein-coupled receptor 55 (HGNC Symbol)
Entrez gene summary	This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013]
Chromosome	2
Cytoband	q37.1
Chromosome location (bp)	230907318 - 230961066
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135898 (version 83.38)
Entrez gene	9290
UniProt	Q9Y2T6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2T6
Antibodypedia	GPR55 antibodies

PROTEIN BROWSER

GPR55-001	GPR55-003	GPR55-201	GPR55-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR55-001 ENSP00000375893 ENST00000392039	Q9Y2T6 [Direct mapping] G-protein coupled receptor 55 A8K858 [Target identity:100%; Query identity:100%] G protein-coupled receptor 55; G protein-coupled receptor 55, isoform CRA_a; cDNA FLJ75410, highly similar to Homo sapiens G protein-coupled receptor 55, mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004949 [cannabinoid receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007202 [activation of phospholipase C activity] GO:0016021 [integral component of membrane] GO:0035025 [positive regulation of Rho protein signal transduction] GO:0038171 [cannabinoid signaling pathway] GO:0045453 [bone resorption] GO:0045671 [negative regulation of osteoclast differentiation] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] Show all	319 aa 36.6 kDa	No	7
GPR55-003 ENSP00000412768 ENST00000438398	C9J1P7 [Direct mapping] G-protein-coupled receptor 55 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	242 aa 27.5 kDa	No	6
GPR55-201 ENSP00000375894 ENST00000392040	Q9Y2T6 [Direct mapping] G-protein coupled receptor 55 A8K858 [Target identity:100%; Query identity:100%] G protein-coupled receptor 55; G protein-coupled receptor 55, isoform CRA_a; cDNA FLJ75410, highly similar to Homo sapiens G protein-coupled receptor 55, mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004949 [cannabinoid receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007202 [activation of phospholipase C activity] GO:0016021 [integral component of membrane] GO:0035025 [positive regulation of Rho protein signal transduction] GO:0038171 [cannabinoid signaling pathway] GO:0045453 [bone resorption] GO:0045671 [negative regulation of osteoclast differentiation] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] Show all	319 aa 36.6 kDa	No	7
GPR55-202 ENSP00000482381 ENST00000622008	Q9Y2T6 [Direct mapping] G-protein coupled receptor 55 A8K858 [Target identity:100%; Query identity:100%] G protein-coupled receptor 55; G protein-coupled receptor 55, isoform CRA_a; cDNA FLJ75410, highly similar to Homo sapiens G protein-coupled receptor 55, mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004949 [cannabinoid receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007202 [activation of phospholipase C activity] GO:0016021 [integral component of membrane] GO:0035025 [positive regulation of Rho protein signal transduction] GO:0038171 [cannabinoid signaling pathway] GO:0045453 [bone resorption] GO:0045671 [negative regulation of osteoclast differentiation] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] Show all	319 aa 36.6 kDa	No	7

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.