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Few cases of prostate and urothelial cancers showed moderate cytoplasmic positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
ADAM10 (HGNC Symbol)
Synonyms
CD156c, HsT18717, kuz, MADM
Description
ADAM metallopeptidase domain 10 (HGNC Symbol)
Entrez gene summary
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. [provided by RefSeq, Jul 2008]