Cell atlas - SLC38A4 - The Human Protein Atlas

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SLC38A4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC38A4
Gene description	Solute carrier family 38, member 4
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (RT4, LHCN-M2, RH-30)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (RT4, LHCN-M2, RH-30) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC38A4 (HGNC Symbol)
Synonyms	ATA3, NAT3, PAAT
Description	Solute carrier family 38, member 4 (HGNC Symbol)
Entrez gene summary	SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001 [PubMed 11342143]).[supplied by OMIM, Mar 2008]
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	46764761 - 46832408
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139209 (version 83.38)
Entrez gene	55089
UniProt	Q969I6 (UniProt - Evidence at protein level)
neXtProt	NX_Q969I6
Antibodypedia	SLC38A4 antibodies

PROTEIN BROWSER

SLC38A4-001	SLC38A4-002	SLC38A4-003	SLC38A4-004	SLC38A4-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC38A4-001 ENSP00000389843 ENST00000447411	Q969I6 [Direct mapping] Sodium-coupled neutral amino acid transporter 4 A0A024R0X7 [Target identity:100%; Query identity:100%] Solute carrier family 38, member 4, isoform CRA_c Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003333 [amino acid transmembrane transport] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006814 [sodium ion transport] GO:0006865 [amino acid transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0015293 [symporter activity] GO:0055085 [transmembrane transport] Show all	547 aa 60.8 kDa	No	>9
SLC38A4-002 ENSP00000266579 ENST00000266579	Q969I6 [Direct mapping] Sodium-coupled neutral amino acid transporter 4 A0A024R0X7 [Target identity:100%; Query identity:100%] Solute carrier family 38, member 4, isoform CRA_c Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003333 [amino acid transmembrane transport] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006814 [sodium ion transport] GO:0006865 [amino acid transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0015293 [symporter activity] GO:0055085 [transmembrane transport] Show all	547 aa 60.8 kDa	No	>9
SLC38A4-003 ENSP00000448543 ENST00000546940	F8VRD9 [Direct mapping] Sodium-coupled neutral amino acid transporter 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005887 [integral component of plasma membrane] GO:0015171 [amino acid transmembrane transporter activity] Show all	192 aa 20.7 kDa	No	3
SLC38A4-004 ENSP00000450071 ENST00000547477	F8VQY9 [Direct mapping] Sodium-coupled neutral amino acid transporter 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005887 [integral component of plasma membrane] GO:0015171 [amino acid transmembrane transporter activity] Show all	219 aa 23.8 kDa	No	5
SLC38A4-005 ENSP00000448186 ENST00000550670	H0YHZ8 [Direct mapping] Sodium-coupled neutral amino acid transporter 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005887 [integral component of plasma membrane] GO:0015171 [amino acid transmembrane transporter activity] Show all	141 aa 15.9 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.