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DPEP3

GENERAL INFORMATION

Gene name

 DPEP3

Gene description

 Dipeptidase 3

Protein class

 Enzymes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA031870 , HPA058607
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 DPEP3

Synonyms

Description

 Dipeptidase 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 q22.1

Chromosome location (bp)

 67975663 - 67980829

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000141096 (version 83.38)

Entrez gene

 64180

UniProt

 Q9H4B8 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9H4B8

Antibodypedia

 DPEP3 antibodies

PROTEIN BROWSER
DPEP3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DPEP3-001
ENSP00000268793
ENST00000268793
Q9H4B8 [Direct mapping]
Dipeptidase 3
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Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Metallopeptidases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0006508 [proteolysis]
GO:0007140 [male meiosis]
GO:0008233 [peptidase activity]
GO:0008235 [metalloexopeptidase activity]
GO:0008239 [dipeptidyl-peptidase activity]
GO:0016020 [membrane]
GO:0016805 [dipeptidase activity]
GO:0031225 [anchored component of membrane]
GO:0046872 [metal ion binding]
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 513 aa
56.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.