Cell atlas - MAPK4 - The Human Protein Atlas

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MAPK4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MAPK4
Gene description	Mitogen-activated protein kinase 4
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H, SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MAPK4 (HGNC Symbol)
Synonyms	Erk3-related, Erk4, PRKM4
Description	Mitogen-activated protein kinase 4 (HGNC Symbol)
Entrez gene summary	Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Chromosome	18
Cytoband
Chromosome location (bp)	50560078 - 50731824
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141639 (version 83.38)
Entrez gene	5596
UniProt	P31152 (UniProt - Evidence at protein level)
neXtProt	NX_P31152
Antibodypedia	MAPK4 antibodies

PROTEIN BROWSER

MAPK4-001	MAPK4-002	MAPK4-003	MAPK4-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAPK4-001 ENSP00000383234 ENST00000400384	P31152 [Direct mapping] Mitogen-activated protein kinase 4 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004707 [MAP kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006468 [protein phosphorylation] GO:0007049 [cell cycle] GO:0019901 [protein kinase binding] GO:0042803 [protein homodimerization activity] GO:0046982 [protein heterodimerization activity] Show all	587 aa 65.9 kDa	No	0
MAPK4-002 ENSP00000466233 ENST00000592595	K7ELV1 [Direct mapping] Mitogen-activated protein kinase 4 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0005622 [intracellular] GO:0006468 [protein phosphorylation] Show all	233 aa 26.2 kDa	No	0
MAPK4-003 ENSP00000465661 ENST00000588540	K7EN18 [Direct mapping] Mitogen-activated protein kinase 4 Show all	Predicted intracellular proteins Show all	GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0005622 [intracellular] GO:0006468 [protein phosphorylation] Show all	281 aa 31.1 kDa	No	0
MAPK4-005 ENSP00000439231 ENST00000540640	B4DEW2 [Direct mapping] Mitogen-activated protein kinase 4; cDNA FLJ50121, highly similar to Homo sapiens mitogen-activated protein kinase 4 (MAPK4), mRNA Show all	Predicted intracellular proteins Show all	GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0005622 [intracellular] GO:0006468 [protein phosphorylation] Show all	376 aa 42.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.