Tissue expression of SYTL5 - Summary - The Human Protein Atlas

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SYTL5

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SYTL5
Gene description	Synaptotagmin-like 5
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (stomach)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (placenta, small intestine)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA026074
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (stomach)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (placenta, small intestine)

GENE INFORMATION
Gene name	SYTL5
Synonyms
Description	Synaptotagmin-like 5 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Chromosome	X
Cytoband	p11.4
Chromosome location (bp)	38006582 - 38128819
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147041 (version 83.38)
Entrez gene	94122
UniProt	Q8TDW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDW5
Antibodypedia	SYTL5 antibodies

PROTEIN BROWSER

SYTL5-001	SYTL5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYTL5-001 ENSP00000297875 ENST00000297875	Q8TDW5 [Direct mapping] Synaptotagmin-like protein 5 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0016079 [synaptic vesicle exocytosis] GO:0017137 [Rab GTPase binding] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] GO:0070382 [exocytic vesicle] Show all	730 aa 81.5 kDa	No	0
SYTL5-201 ENSP00000395220 ENST00000456733	Q8TDW5 [Direct mapping] Synaptotagmin-like protein 5 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006887 [exocytosis] GO:0016079 [synaptic vesicle exocytosis] GO:0017137 [Rab GTPase binding] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] GO:0070382 [exocytic vesicle] Show all	752 aa 83.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.