Cell atlas - THYN1 - The Human Protein Atlas

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THYN1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli fibrillar center
	Nucleus

Human cell
	Cytosol
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	THYN1
Gene description	Thymocyte nuclear protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus & nucleoli (fibrillar center). In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported), Nucleoli fibrillar center (supported)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA038732 , HPA038733
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus & nucleoli (fibrillar center). In addition localized to the cytosol.

Main location

Nucleus (supported), Nucleoli fibrillar center (supported)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA038732	A-431	Nucleus
HPA038732	A-431	Nucleoli fibrillar center
HPA038732	U-2 OS	Nucleus
HPA038732	U-2 OS	Nucleoli fibrillar center
HPA038732	U-251 MG	Nucleus
HPA038732	U-251 MG	Nucleoli fibrillar center
HPA038733	CACO-2	Nucleus
		Nucleoli fibrillar center
		Cytosol
HPA038733	U-2 OS	No staining
HPA038733	U-251 MG	Nucleus
		Nucleoli fibrillar center
		Cytosol

GENE INFORMATION
Gene name	THYN1 (HGNC Symbol)
Synonyms	THY28
Description	Thymocyte nuclear protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is highly conserved among vertebrates and plant species and may be involved in the induction of apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q25
Chromosome location (bp)	134248279 - 134253370
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151500 (version 83.38)
Entrez gene	29087
UniProt	Q9P016 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P016
Antibodypedia	THYN1 antibodies

PROTEIN BROWSER

THYN1-001	THYN1-002	THYN1-004	THYN1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
THYN1-001 ENSP00000341452 ENST00000352327	Q9P016 [Direct mapping] Thymocyte nuclear protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	166 aa 18.8 kDa	No	0
THYN1-002 ENSP00000341657 ENST00000341541	Q9P016 [Direct mapping] Thymocyte nuclear protein 1 A0A024R3M1 [Target identity:100%; Query identity:100%] Thymocyte nuclear protein 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	225 aa 25.7 kDa	No	0
THYN1-004 ENSP00000376373 ENST00000392594	Q9P016 [Direct mapping] Thymocyte nuclear protein 1 A0A024R3M1 [Target identity:100%; Query identity:100%] Thymocyte nuclear protein 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	225 aa 25.7 kDa	No	0
THYN1-005 ENSP00000376374 ENST00000392595	Q9P016 [Direct mapping] Thymocyte nuclear protein 1 A0A024R3M1 [Target identity:100%; Query identity:100%] Thymocyte nuclear protein 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	225 aa 25.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.