Cell atlas - FAM213B - The Human Protein Atlas

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FAM213B

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Plasma membrane

Human cell
	Cytosol
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	FAM213B
Gene description	Family with sequence similarity 213, member B
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the plasma membrane & nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)
Additional location	In addition localized to the Nucleoplasm (approved), Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA006403
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the plasma membrane & nucleoplasm.

Main location

Cytosol (approved)

Additional location

Nucleoplasm (approved), Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA006403	A-431	Nucleoplasm
	HPA006403	A-431	Cytosol
	HPA006403	PC-3	Nucleoplasm
	HPA006403	PC-3	Cytosol
	HPA006403	U-2 OS	Nucleoplasm
			Plasma membrane
			Cytosol

GENE INFORMATION
Gene name	FAM213B (HGNC Symbol)
Synonyms	C1orf93, MGC26818
Description	Family with sequence similarity 213, member B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.32
Chromosome location (bp)	2586491 - 2591469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157870 (version 83.38)
Entrez gene	127281
UniProt	Q8TBF2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TBF2
Antibodypedia	FAM213B antibodies

PROTEIN BROWSER

FAM213B-001	FAM213B-002	FAM213B-003	FAM213B-010	FAM213B-011	FAM213B-014	FAM213B-201	FAM213B-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM213B-001 ENSP00000394405 ENST00000419916	Q8TBF2 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0019369 [arachidonic acid metabolic process] GO:0019371 [cyclooxygenase pathway] GO:0043209 [myelin sheath] GO:0044281 [small molecule metabolic process] GO:0047017 [prostaglandin-F synthase activity] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	228 aa 24.3 kDa	No	0
FAM213B-002 ENSP00000367681 ENST00000378424	J3KPF5 [Direct mapping] Prostamide/prostaglandin F synthase Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		231 aa 24.7 kDa	No	0
FAM213B-003 ENSP00000367684 ENST00000378427	J3KPF6 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		213 aa 22.4 kDa	No	0
FAM213B-010 ENSP00000463127 ENST00000498083	J3QKK8 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 16.5 kDa	No	0
FAM213B-011 ENSP00000462185 ENST00000465233	J3KRV9 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		197 aa 20.9 kDa	No	0
FAM213B-014 ENSP00000443605 ENST00000537325	Q8TBF2 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0019369 [arachidonic acid metabolic process] GO:0019371 [cyclooxygenase pathway] GO:0043209 [myelin sheath] GO:0044281 [small molecule metabolic process] GO:0047017 [prostaglandin-F synthase activity] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	191 aa 20.5 kDa	No	0
FAM213B-201 ENSP00000367682 ENST00000378425	A0A0A0MRV4 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		192 aa 20.7 kDa	No	0
FAM213B-202 ENSP00000413218 ENST00000444521	A0A0A0MT35 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0043209 [myelin sheath] Show all	246 aa 26.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.