Expression of FAM213B in cancer - Summary - The Human Protein Atlas

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FAM213B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM213B
Gene description	Family with sequence similarity 213, member B
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA006403
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA006403

GENE INFORMATION
Gene name	FAM213B (HGNC Symbol)
Synonyms	C1orf93, MGC26818
Description	Family with sequence similarity 213, member B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.32
Chromosome location (bp)	2586491 - 2591469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157870 (version 83.38)
Entrez gene	127281
UniProt	Q8TBF2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TBF2
Antibodypedia	FAM213B antibodies

PROTEIN BROWSER

FAM213B-001	FAM213B-002	FAM213B-003	FAM213B-010	FAM213B-011	FAM213B-014	FAM213B-201	FAM213B-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM213B-001 ENSP00000394405 ENST00000419916	Q8TBF2 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0019369 [arachidonic acid metabolic process] GO:0019371 [cyclooxygenase pathway] GO:0043209 [myelin sheath] GO:0044281 [small molecule metabolic process] GO:0047017 [prostaglandin-F synthase activity] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	228 aa 24.3 kDa	No	0
FAM213B-002 ENSP00000367681 ENST00000378424	J3KPF5 [Direct mapping] Prostamide/prostaglandin F synthase Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		231 aa 24.7 kDa	No	0
FAM213B-003 ENSP00000367684 ENST00000378427	J3KPF6 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		213 aa 22.4 kDa	No	0
FAM213B-010 ENSP00000463127 ENST00000498083	J3QKK8 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 16.5 kDa	No	0
FAM213B-011 ENSP00000462185 ENST00000465233	J3KRV9 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		197 aa 20.9 kDa	No	0
FAM213B-014 ENSP00000443605 ENST00000537325	Q8TBF2 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0019369 [arachidonic acid metabolic process] GO:0019371 [cyclooxygenase pathway] GO:0043209 [myelin sheath] GO:0044281 [small molecule metabolic process] GO:0047017 [prostaglandin-F synthase activity] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	191 aa 20.5 kDa	No	0
FAM213B-201 ENSP00000367682 ENST00000378425	A0A0A0MRV4 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		192 aa 20.7 kDa	No	0
FAM213B-202 ENSP00000413218 ENST00000444521	A0A0A0MT35 [Direct mapping] Prostamide/prostaglandin F synthase Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0043209 [myelin sheath] Show all	246 aa 26.4 kDa	No	0

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The Human Protein Atlas

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