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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

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Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

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Score

Score

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Antibodies

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ABHD3
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ABHD3

Gene description

Abhydrolase domain containing 3

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA010729
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Lung

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ABHD3 (HGNC Symbol)

Synonyms

LABH3

Description

Abhydrolase domain containing 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q11.2

Chromosome location (bp)

21650897 - 21704805

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158201 (version 83.38)

Entrez gene

171586

UniProt

Q8WU67 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WU67

Antibodypedia

ABHD3 antibodies

PROTEIN BROWSER

ABHD3-001
ABHD3-002
ABHD3-003
ABHD3-007
ABHD3-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABHD3-001
ENSP00000289119
ENST00000289119
Q8WU67 [Direct mapping]
Phospholipase ABHD3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004623 [phospholipase A2 activity]
GO:0005575 [cellular_component]
GO:0005886 [plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0008970 [phosphatidylcholine 1-acylhydrolase activity]
GO:0016021 [integral component of membrane]
GO:0044281 [small molecule metabolic process]
GO:0046470 [phosphatidylcholine metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0052739 [phosphatidylserine 1-acylhydrolase activity]
GO:0052740 [1-acyl-2-lysophosphatidylserine acylhydrolase activity]
Show all
409 aa
46 kDa
No 2
ABHD3-002
ENSP00000462578
ENST00000578270
J3KSP1 [Direct mapping]
Phospholipase ABHD3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
214 aa
24.4 kDa
No 0
ABHD3-003
ENSP00000462935
ENST00000580981
J3KTE1 [Direct mapping]
Phospholipase ABHD3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
356 aa
40.4 kDa
No 1
ABHD3-007
ENSP00000463848
ENST00000584464
J3QQR0 [Direct mapping]
Phospholipase ABHD3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
112 aa
12.6 kDa
No 0
ABHD3-009
ENSP00000463996
ENST00000580477
J3QR14 [Direct mapping]
Phospholipase ABHD3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
37 aa
3.8 kDa
No 0

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The Human Protein Atlas project is funded
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