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ITLN2

GENERAL INFORMATION

Gene name

 ITLN2

Gene description

 Intelectin 2

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (duodenum, small intestine)
GTEx:Tissue enriched (small intestine)
FANTOM5:Group enriched (colon, small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Extracellular positivity in goblet cells, mainly in small intestine and duodenum.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

 Approved based on 1 antibody.
HPA006683
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Small intestine

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (duodenum, small intestine)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (small intestine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, small intestine)

GENE INFORMATION

Gene name

 ITLN2 (HGNC Symbol)

Synonyms

 HL-2

Description

 Intelectin 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q23.3

Chromosome location (bp)

 160945025 - 160954799

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000158764 (version 83.38)

Entrez gene

 142683

UniProt

 Q8WWU7 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8WWU7

Antibodypedia

 ITLN2 antibodies

PROTEIN BROWSER
ITLN2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ITLN2-001
ENSP00000357008
ENST00000368029
Q8WWU7 [Direct mapping]
Intelectin-2
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   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
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GO:0005576 [extracellular region]
GO:0030246 [carbohydrate binding]
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 325 aa
36.2 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.