We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Colorectal cancer and a few cases of gastric cancer showed moderate to strong nuclear immunoreactivity. Other malignancies were negative.
GENE INFORMATION
Gene name
CDX2 (HGNC Symbol)
Synonyms
CDX3
Description
Caudal type homeobox 2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]