Tissue expression of TTC7B - Summary - The Human Protein Atlas

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TTC7B

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TTC7B
Gene description	Tetratricopeptide repeat domain 7B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Distinct expression in brain. Membranous expression in most tissues, highly abundant in placenta, stomach and renal tubules.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA058363 , HPA059577
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TTC7B (HGNC Symbol)
Synonyms	TTC7L1
Description	Tetratricopeptide repeat domain 7B (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.11
Chromosome location (bp)	90524564 - 90816479
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165914 (version 83.38)
Entrez gene	145567
UniProt	Q86TV6 (UniProt - Evidence at protein level)
neXtProt	NX_Q86TV6
Antibodypedia	TTC7B antibodies

PROTEIN BROWSER

TTC7B-001	TTC7B-004	TTC7B-005	TTC7B-009	TTC7B-012	TTC7B-013	TTC7B-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TTC7B-001 ENSP00000336127 ENST00000328459	Q86TV6 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	843 aa 94.2 kDa	No	0
TTC7B-004 ENSP00000451201 ENST00000553948	G3V3E4 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		48 aa 5.4 kDa	No	0
TTC7B-005 ENSP00000451238 ENST00000557766	G3V3H1 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		205 aa 23.5 kDa	No	0
TTC7B-009 ENSP00000451928 ENST00000554462	H0YJP9 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	175 aa 19.5 kDa	No	0
TTC7B-012 ENSP00000452594 ENST00000555894	H0YK02 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		213 aa 22.3 kDa	No	0
TTC7B-013 ENSP00000452031 ENST00000557292	H0YJS2 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	271 aa 29.3 kDa	No	0
TTC7B-015 ENSP00000451440 ENST00000553972	A0A0C4DGK5 [Direct mapping] Tetratricopeptide repeat protein 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	330 aa 36.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.