Cell atlas - NELL1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NELL1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	NELL1
Gene description	Neural EGFL like 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SH-SY5Y, WM-115, U-2 OS)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, WM-115, U-2 OS) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	NELL1 (HGNC Symbol)
Synonyms	FLJ45906, IDH3GL
Description	Neural EGFL like 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Chromosome	11
Cytoband	p15.1
Chromosome location (bp)	20669551 - 21575681
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165973 (version 83.38)
Entrez gene	4745
UniProt	Q92832 (UniProt - Evidence at protein level)
neXtProt	NX_Q92832
Antibodypedia	NELL1 antibodies

PROTEIN BROWSER

NELL1-001	NELL1-002	NELL1-003	NELL1-201	NELL1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NELL1-001 ENSP00000349654 ENST00000357134	Q92832 [Direct mapping] Protein kinase C-binding protein NELL1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0010468 [regulation of gene expression] GO:0030154 [cell differentiation] GO:0030501 [positive regulation of bone mineralization] GO:0033689 [negative regulation of osteoblast proliferation] GO:0045669 [positive regulation of osteoblast differentiation] GO:0048471 [perinuclear region of cytoplasm] GO:2000599 [negative regulation of cyclin catabolic process] Show all	810 aa 89.6 kDa	Yes	0
NELL1-002 ENSP00000298925 ENST00000298925	J3KNC5 [Direct mapping] NEL-like 1 (Chicken), isoform CRA_a; Protein kinase C-binding protein NELL1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	838 aa 92.8 kDa	Yes	0
NELL1-003 ENSP00000437170 ENST00000532434	Q92832 [Direct mapping] Protein kinase C-binding protein NELL1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0010468 [regulation of gene expression] GO:0030154 [cell differentiation] GO:0030501 [positive regulation of bone mineralization] GO:0033689 [negative regulation of osteoblast proliferation] GO:0045669 [positive regulation of osteoblast differentiation] GO:0048471 [perinuclear region of cytoplasm] GO:2000599 [negative regulation of cyclin catabolic process] Show all	763 aa 84.4 kDa	Yes	0
NELL1-201 ENSP00000317837 ENST00000325319	F5H6I3 [Direct mapping] Protein kinase C-binding protein NELL1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	753 aa 83 kDa	Yes	0
NELL1-202 ENSP00000479479 ENST00000619031	K9UUD5 [Direct mapping] NELL-1 protein short isoform; Protein kinase C-binding protein NELL1 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	570 aa 62.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.