Cell atlas - CTRB1 - The Human Protein Atlas

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CTRB1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CTRB1
Gene description	Chymotrypsinogen B1
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (EFO-21, U-2 OS, HDLM-2)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CTRB1 (HGNC Symbol)
Synonyms	CTRB
Description	Chymotrypsinogen B1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011]
Chromosome	16
Cytoband	q23.1
Chromosome location (bp)	75219000 - 75224924
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000168925 (version 83.38)
Entrez gene	1504
UniProt	P17538 (UniProt - Evidence at transcript level)
neXtProt	NX_P17538
Antibodypedia	CTRB1 antibodies

PROTEIN BROWSER

CTRB1-001	CTRB1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTRB1-001 ENSP00000354294 ENST00000361017	P17538 [Direct mapping] Chymotrypsinogen B Chymotrypsin B chain A Chymotrypsin B chain B Chymotrypsin B chain C Show all	Enzymes ENZYME proteins Hydrolases Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0007586 [digestion] GO:0009235 [cobalamin metabolic process] GO:0022617 [extracellular matrix disassembly] GO:0030198 [extracellular matrix organization] GO:0044281 [small molecule metabolic process] Show all	263 aa 27.7 kDa	Yes	0
CTRB1-002 ENSP00000463301 ENST00000495583	J3QKZ2 [Direct mapping] Chymotrypsinogen B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	182 aa 19.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.