Tissue expression of CTRB1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CTRB1
Gene description	Chymotrypsinogen B1
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (pancreas)
GTEx:	Tissue enriched (pancreas)
FANTOM5:	Tissue enriched (pancreas)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)

GENE INFORMATION
Gene name	CTRB1 (HGNC Symbol)
Synonyms	CTRB
Description	Chymotrypsinogen B1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011]
Chromosome	16
Cytoband	q23.1
Chromosome location (bp)	75219000 - 75224924
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000168925 (version 83.38)
Entrez gene	1504
UniProt	P17538 (UniProt - Evidence at transcript level)
neXtProt	NX_P17538
Antibodypedia	CTRB1 antibodies

PROTEIN BROWSER

CTRB1-001	CTRB1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTRB1-001 ENSP00000354294 ENST00000361017	P17538 [Direct mapping] Chymotrypsinogen B Chymotrypsin B chain A Chymotrypsin B chain B Chymotrypsin B chain C Show all	Enzymes ENZYME proteins Hydrolases Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0007586 [digestion] GO:0009235 [cobalamin metabolic process] GO:0022617 [extracellular matrix disassembly] GO:0030198 [extracellular matrix organization] GO:0044281 [small molecule metabolic process] Show all	263 aa 27.7 kDa	Yes	0
CTRB1-002 ENSP00000463301 ENST00000495583	J3QKZ2 [Direct mapping] Chymotrypsinogen B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	182 aa 19.4 kDa	No	0