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Gene name

Class

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Chromosome

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In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

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Cell type

Expression

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Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

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Detectable

Cancer

Detectable

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PLA2G16
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PLA2G16

Gene description

Phospholipase A2, group XVI

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene. Antibody staining mainly not consistent with RNA expression data.

Reliability score

Uncertain based on 1 antibody.
HPA058997
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW

RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

PLA2G16 (HGNC Symbol)

Synonyms

AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754.

Description

Phospholipase A2, group XVI (HGNC Symbol)

Entrez gene summary

Chromosome

11

Cytoband

Chromosome location (bp)

63573195 - 63616883

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176485 (version 83.38)

Entrez gene

11145

UniProt

P53816 (UniProt - Evidence at protein level)

neXtProt

NX_P53816

Antibodypedia

PLA2G16 antibodies

PROTEIN BROWSER

PLA2G16-001
PLA2G16-003
PLA2G16-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLA2G16-001
ENSP00000320337
ENST00000323646
P53816 [Direct mapping]
HRAS-like suppressor 3
A0A024R561 [Target identity:100%; Query identity:100%]
HRAS-like suppressor 3, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004623 [phospholipase A2 activity]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0006644 [phospholipid metabolic process]
GO:0008654 [phospholipid biosynthetic process]
GO:0008970 [phosphatidylcholine 1-acylhydrolase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016042 [lipid catabolic process]
GO:0036149 [phosphatidylinositol acyl-chain remodeling]
GO:0036150 [phosphatidylserine acyl-chain remodeling]
GO:0036151 [phosphatidylcholine acyl-chain remodeling]
GO:0036152 [phosphatidylethanolamine acyl-chain remodeling]
GO:0044281 [small molecule metabolic process]
GO:0045786 [negative regulation of cell cycle]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0052739 [phosphatidylserine 1-acylhydrolase activity]
GO:0052740 [1-acyl-2-lysophosphatidylserine acylhydrolase activity]
Show all
162 aa
17.9 kDa
No 1
PLA2G16-003
ENSP00000442576
ENST00000540943
F5H7E5 [Direct mapping]
HRAS-like suppressor 3
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
27 aa
3 kDa
No 0
PLA2G16-201
ENSP00000389124
ENST00000415826
P53816 [Direct mapping]
HRAS-like suppressor 3
A0A024R561 [Target identity:100%; Query identity:100%]
HRAS-like suppressor 3, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004623 [phospholipase A2 activity]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005829 [cytosol]
GO:0006644 [phospholipid metabolic process]
GO:0008970 [phosphatidylcholine 1-acylhydrolase activity]
GO:0016021 [integral component of membrane]
GO:0016042 [lipid catabolic process]
GO:0036149 [phosphatidylinositol acyl-chain remodeling]
GO:0036150 [phosphatidylserine acyl-chain remodeling]
GO:0036151 [phosphatidylcholine acyl-chain remodeling]
GO:0036152 [phosphatidylethanolamine acyl-chain remodeling]
GO:0044281 [small molecule metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0052739 [phosphatidylserine 1-acylhydrolase activity]
GO:0052740 [1-acyl-2-lysophosphatidylserine acylhydrolase activity]
Show all
162 aa
17.9 kDa
No 1

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