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SYCP2

GENERAL INFORMATION

Gene name

 SYCP2

Gene description

 Synaptonemal complex protein 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (breast cancer, cervical cancer)
HPA (cell line):Cell line enhanced (MOLT-4, SiHa, T-47d)
HPA (normal tissue):Group enriched (breast, testis)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (breast cancer, cervical cancer)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 SYCP2 (HGNC Symbol)

Synonyms

 SCP2

Description

 Synaptonemal complex protein 2 (HGNC Symbol)

Entrez gene summary

 The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q13.33

Chromosome location (bp)

 59863563 - 59933655

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196074 (version 83.38)

Entrez gene

 10388

UniProt

 Q9BX26 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9BX26

Antibodypedia

 SYCP2 antibodies

PROTEIN BROWSER
SYCP2-001
SYCP2-002
SYCP2-003
SYCP2-008
SYCP2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SYCP2-001
ENSP00000350162
ENST00000357552
Q9BX26 [Direct mapping]
Synaptonemal complex protein 2
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Predicted intracellular proteins
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GO:0000795 [synaptonemal complex]
GO:0000800 [lateral element]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0007130 [synaptonemal complex assembly]
GO:0007140 [male meiosis]
GO:0007143 [female meiotic division]
GO:0009566 [fertilization]
GO:0009887 [organ morphogenesis]
GO:0043066 [negative regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0048808 [male genitalia morphogenesis]
GO:0051301 [cell division]
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 1530 aa
175.6 kDa 		No 0
SYCP2-002
ENSP00000402456
ENST00000446834
A2A341 [Direct mapping]
Synaptonemal complex protein 2
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Predicted intracellular proteins
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 1023 aa
116.5 kDa 		No 0
SYCP2-003
ENSP00000399300
ENST00000425931
A2A2M9 [Direct mapping]
Synaptonemal complex protein 2
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Predicted intracellular proteins
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 118 aa
13.4 kDa 		No 0
SYCP2-008
ENSP00000404358
ENST00000412613
A2A340 [Direct mapping]
Synaptonemal complex protein 2
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Predicted intracellular proteins
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 208 aa
25.1 kDa 		No 0
SYCP2-201
ENSP00000360040
ENST00000371001
Q9BX26 [Direct mapping]
Synaptonemal complex protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0000795 [synaptonemal complex]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007130 [synaptonemal complex assembly]
GO:0051301 [cell division]
Show all
 1530 aa
175.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.