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SERPINA1
  • premium

    TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

SERPINA1

Gene description

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Protein class

Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

15
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (liver)
GTEx:Tissue enriched (liver)
FANTOM5:Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein expression

Distinct positivity in plasma and expression in extracellular matrix in a majority of tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

Supported based on 5 antibodies.
HPA000927 , HPA001292 , CAB013211 , CAB016648 , CAB073396
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
N/A
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
N/A
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
N/A
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Lung

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (liver)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (liver)

GENE INFORMATION

Gene name

SERPINA1 (HGNC Symbol)

Synonyms

A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1

Description

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.13

Chromosome location (bp)

94376747 - 94390693

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197249 (version 83.38)

Entrez gene

5265

UniProt

P01009 (UniProt - Evidence at protein level)

neXtProt

NX_P01009

Antibodypedia

SERPINA1 antibodies

PROTEIN BROWSER

«
SERPINA1-001
SERPINA1-002
SERPINA1-003
SERPINA1-004
SERPINA1-006
SERPINA1-007
SERPINA1-008
SERPINA1-010
SERPINA1-011
SERPINA1-015
SERPINA1-016
SERPINA1-017
SERPINA1-201
SERPINA1-202
SERPINA1-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINA1-001
ENSP00000390299
ENST00000440909
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-002
ENSP00000376803
ENST00000393088
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-003
ENSP00000385960
ENST00000404814
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-004
ENSP00000376802
ENST00000393087
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-006
ENSP00000386094
ENST00000402629
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
359 aa
40.3 kDa
Yes 0
SERPINA1-007
ENSP00000452452
ENST00000557492
A0A0B4J278 [Direct mapping]
Alpha-1-antitrypsin
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010951 [negative regulation of endopeptidase activity]
Show all
144 aa
15.7 kDa
Yes 0
SERPINA1-008
ENSP00000416354
ENST00000449399
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-010
ENSP00000451826
ENST00000557118
G3V4I7 [Direct mapping]
Alpha-1-antitrypsin
Show all
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0010951 [negative regulation of endopeptidase activity]
Show all
22 aa
2.2 kDa
Yes 0
SERPINA1-011
ENSP00000451098
ENST00000556955
G3V387 [Direct mapping]
Alpha-1-antitrypsin
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010951 [negative regulation of endopeptidase activity]
Show all
117 aa
12.7 kDa
Yes 0
SERPINA1-015
ENSP00000452480
ENST00000553327
G3V5R8 [Direct mapping]
Alpha-1-antitrypsin
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010951 [negative regulation of endopeptidase activity]
Show all
92 aa
9.9 kDa
Yes 0
SERPINA1-016
ENSP00000450561
ENST00000554720
G3V2B9 [Direct mapping]
Alpha-1-antitrypsin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010951 [negative regulation of endopeptidase activity]
Show all
105 aa
11.8 kDa
No 0
SERPINA1-017
ENSP00000452169
ENST00000556091
G3V544 [Direct mapping]
Alpha-1-antitrypsin
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0010951 [negative regulation of endopeptidase activity]
Show all
156 aa
17.1 kDa
Yes 0
SERPINA1-201
ENSP00000348068
ENST00000355814
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-202
ENSP00000408474
ENST00000437397
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0
SERPINA1-203
ENSP00000416066
ENST00000448921
P01009 [Direct mapping]
Alpha-1-antitrypsin Short peptide from AAT
E9KL23 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 44a
Show all
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001948 [glycoprotein binding]
GO:0002020 [protease binding]
GO:0002576 [platelet degranulation]
GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006953 [acute-phase response]
GO:0007596 [blood coagulation]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030168 [platelet activation]
GO:0031093 [platelet alpha granule lumen]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0042802 [identical protein binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
418 aa
46.7 kDa
Yes 0

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