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TRIM31

GENERAL INFORMATION

Gene name

 TRIM31

Gene description

 Tripartite motif containing 31

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (colon, small intestine, stomach, urinary bladder)
GTEx:Group enriched (colon, small intestine, stomach, testis, urinary bladder)
FANTOM5:Tissue enhanced (appendix, colon, small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplsmic expression.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA046400
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, small intestine, stomach, urinary bladder)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, small intestine, stomach, testis, urinary bladder)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (appendix, colon, small intestine)

GENE INFORMATION

Gene name

 TRIM31 (HGNC Symbol)

Synonyms

 C6orf13, HCG1, HCGI, RNF

Description

 Tripartite motif containing 31 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified. [provided by RefSeq, Jul 2008]

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 30102897 - 30113106

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204616 (version 83.38)

Entrez gene

 11074

UniProt

 Q9BZY9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BZY9

Antibodypedia

 TRIM31 antibodies

PROTEIN BROWSER
TRIM31-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM31-001
ENSP00000365924
ENST00000376734
Q9BZY9 [Direct mapping]
E3 ubiquitin-protein ligase TRIM31
Q2L6J1 [Target identity:100%; Query identity:100%]
Tripartite motif-containing 31; cDNA FLJ75322, highly similar to Homo sapiens tripartite motif-containing 31, transcript variant 1, mRNA
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0032897 [negative regulation of viral transcription]
GO:0045087 [innate immune response]
GO:0046597 [negative regulation of viral entry into host cell]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1902186 [regulation of viral release from host cell]
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 425 aa
48.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.