Cell atlas - CAPN14 - The Human Protein Atlas

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CAPN14

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CAPN14
Gene description	Calpain 14
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-266/70)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-266/70) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CAPN14
Synonyms
Description	Calpain 14 (HGNC Symbol)
Entrez gene summary	Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	p23.1
Chromosome location (bp)	31173056 - 31233858
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000214711 (version 83.38)
Entrez gene	440854
UniProt	A8MX76 (UniProt - Evidence at transcript level)
neXtProt	NX_A8MX76
Antibodypedia	CAPN14 antibodies

PROTEIN BROWSER

CAPN14-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CAPN14-002 ENSP00000385247 ENST00000403897	A8MX76 [Direct mapping] Calpain-14 Show all	Enzymes Peptidases Cysteine-type peptidases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005509 [calcium ion binding] GO:0005622 [intracellular] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	684 aa 79.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.