Tissue expression of CAPN14 - Summary - The Human Protein Atlas

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CAPN14

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CAPN14
Gene description	Calpain 14
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (esophagus)
GTEx:	Tissue enriched (esophagus)
FANTOM5:	Group enriched (esophagus, tonsil)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (esophagus)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (esophagus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, tonsil)

GENE INFORMATION
Gene name	CAPN14
Synonyms
Description	Calpain 14 (HGNC Symbol)
Entrez gene summary	Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	p23.1
Chromosome location (bp)	31173056 - 31233858
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000214711 (version 83.38)
Entrez gene	440854
UniProt	A8MX76 (UniProt - Evidence at transcript level)
neXtProt	NX_A8MX76
Antibodypedia	CAPN14 antibodies

PROTEIN BROWSER

CAPN14-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CAPN14-002 ENSP00000385247 ENST00000403897	A8MX76 [Direct mapping] Calpain-14 Show all	Enzymes Peptidases Cysteine-type peptidases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005509 [calcium ion binding] GO:0005622 [intracellular] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	684 aa 79.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.