Tissue expression of MYL5 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MYL5

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	MYL5
Gene description	Myosin, light chain 5, regulatory
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 2 antibodies. HPA037381 , HPA039262
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	MYL5
Synonyms
Description	Myosin, light chain 5, regulatory (HGNC Symbol)
Entrez gene summary	This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	673580 - 682033
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215375 (version 83.38)
Entrez gene	4636
UniProt	Q02045 (UniProt - Evidence at transcript level)
neXtProt	NX_Q02045
Antibodypedia	MYL5 antibodies

PROTEIN BROWSER

MYL5-001	MYL5-002	MYL5-004	MYL5-008	MYL5-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYL5-001 ENSP00000383023 ENST00000400159	Q02045 [Direct mapping] Myosin light chain 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005829 [cytosol] GO:0005859 [muscle myosin complex] GO:0006936 [muscle contraction] GO:0006937 [regulation of muscle contraction] GO:0008307 [structural constituent of muscle] Show all	173 aa 19.5 kDa	No	0
MYL5-002 ENSP00000427153 ENST00000506838	Q02045 [Direct mapping] Myosin light chain 5 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005829 [cytosol] GO:0005859 [muscle myosin complex] GO:0006936 [muscle contraction] GO:0006937 [regulation of muscle contraction] GO:0008307 [structural constituent of muscle] Show all	132 aa 14.9 kDa	No	0
MYL5-004 ENSP00000425162 ENST00000511290	Q02045 [Direct mapping] Myosin light chain 5 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005829 [cytosol] GO:0005859 [muscle myosin complex] GO:0006936 [muscle contraction] GO:0006937 [regulation of muscle contraction] GO:0008307 [structural constituent of muscle] Show all	132 aa 14.9 kDa	No	0
MYL5-008 ENSP00000427317 ENST00000507804	D6RJ91 [Direct mapping] Myosin light chain 5 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] Show all	126 aa 14.1 kDa	No	0
MYL5-009 ENSP00000423118 ENST00000505477	Q02045 [Direct mapping] Myosin light chain 5 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005829 [cytosol] GO:0005859 [muscle myosin complex] GO:0006936 [muscle contraction] GO:0006937 [regulation of muscle contraction] GO:0008307 [structural constituent of muscle] Show all	132 aa 14.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.