Tissue expression of PKD1L3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PKD1L3
Gene description	Polycystic kidney disease 1-like 3
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
FANTOM5:	Not detected

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	PKD1L3
Synonyms
Description	Polycystic kidney disease 1-like 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009]
Chromosome	16
Cytoband	q22.2
Chromosome location (bp)	71929538 - 71999978
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000277481 (version 83.38)
Entrez gene	342372
UniProt	Q7Z443 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z443
Antibodypedia	PKD1L3 antibodies

PROTEIN BROWSER

PKD1L3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PKD1L3-001 ENSP00000480090 ENST00000620267	Q7Z443 [Direct mapping] Polycystic kidney disease protein 1-like 3 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0001581 [detection of chemical stimulus involved in sensory perception of sour taste] GO:0001822 [kidney development] GO:0005261 [cation channel activity] GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0009986 [cell surface] GO:0016020 [membrane] GO:0030246 [carbohydrate binding] GO:0033040 [sour taste receptor activity] GO:0034703 [cation channel complex] GO:0043235 [receptor complex] GO:0050915 [sensory perception of sour taste] GO:0070062 [extracellular exosome] GO:0070588 [calcium ion transmembrane transport] GO:0071468 [cellular response to acidic pH] GO:0098655 [cation transmembrane transport] Show all	1732 aa 195.9 kDa	No	>9