Cell atlas - ABLIM1 - The Human Protein Atlas

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ABLIM1

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	ABLIM1
Gene description	Actin binding LIM protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA038952
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA038952	A-431	Cytosol
	HPA038952	U-2 OS	Cytosol
	HPA038952	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ABLIM1 (HGNC Symbol)
Synonyms	ABLIM, LIMAB1, limatin
Description	Actin binding LIM protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q25.3
Chromosome location (bp)	114431113 - 114685003
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000099204 (version 83.38)
Entrez gene	3983
UniProt	O14639 (UniProt - Evidence at protein level)
neXtProt	NX_O14639
Antibodypedia	ABLIM1 antibodies

PROTEIN BROWSER

ABLIM1-001	ABLIM1-002	ABLIM1-005	ABLIM1-009	ABLIM1-010	ABLIM1-011	ABLIM1-012	ABLIM1-201	ABLIM1-202	ABLIM1-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABLIM1-001 ENSP00000277895 ENST00000277895	O14639 [Direct mapping] Actin-binding LIM protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0015629 [actin cytoskeleton] GO:0030027 [lamellipodium] GO:0030032 [lamellipodium assembly] GO:0042384 [cilium assembly] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0097481 [neuronal postsynaptic density] Show all	778 aa 87.7 kDa	No	0
ABLIM1-002 ENSP00000376682 ENST00000392955	O14639 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0015629 [actin cytoskeleton] GO:0030027 [lamellipodium] GO:0030032 [lamellipodium assembly] GO:0042384 [cilium assembly] Show all	718 aa 81.1 kDa	No	0
ABLIM1-005 ENSP00000358260 ENST00000369256	O14639 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0015629 [actin cytoskeleton] GO:0030027 [lamellipodium] GO:0030032 [lamellipodium assembly] GO:0042384 [cilium assembly] Show all	748 aa 84.6 kDa	No	0
ABLIM1-009 ENSP00000376679 ENST00000392952	O14639 [Direct mapping] Actin-binding LIM protein 1 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0015629 [actin cytoskeleton] GO:0030027 [lamellipodium] GO:0030032 [lamellipodium assembly] GO:0042384 [cilium assembly] Show all	455 aa 52.1 kDa	No	0
ABLIM1-010 ENSP00000358257 ENST00000369253	O14639 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0015629 [actin cytoskeleton] GO:0030027 [lamellipodium] GO:0030032 [lamellipodium assembly] GO:0042384 [cilium assembly] Show all	401 aa 46.1 kDa	No	0
ABLIM1-011 ENSP00000400934 ENST00000428430	F6XFR5 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		173 aa 19.8 kDa	No	0
ABLIM1-012 ENSP00000414154 ENST00000440467	H0Y7N6 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		172 aa 19.6 kDa	No	0
ABLIM1-201 ENSP00000358256 ENST00000369252	A0A0A0MRL6 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0007010 [cytoskeleton organization] GO:0008270 [zinc ion binding] Show all	746 aa 84.4 kDa	No	0
ABLIM1-202 ENSP00000358270 ENST00000369266	J3QSX6 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0007010 [cytoskeleton organization] Show all	401 aa 46.1 kDa	No	0
ABLIM1-203 ENSP00000433629 ENST00000533213	F8W8M4 [Direct mapping] Actin-binding LIM protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0007010 [cytoskeleton organization] GO:0008270 [zinc ion binding] Show all	718 aa 81.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.