We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Caution, targets protein from more than one gene. Correlation with RNA expression data cannot be evaluated due to technical limitations (poly-A tail missing).
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation. [provided by RefSeq, Oct 2015]
Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000784 [nuclear chromosome, telomeric region] GO:0000785 [chromatin] GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001740 [Barr body] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006334 [nucleosome assembly] GO:0006342 [chromatin silencing] GO:0007420 [brain development] GO:0007549 [dosage compensation] GO:0016568 [chromatin modification] GO:0031490 [chromatin DNA binding] GO:0035098 [ESC/E(Z) complex] GO:0044212 [transcription regulatory region DNA binding] GO:0045618 [positive regulation of keratinocyte differentiation] GO:0045814 [negative regulation of gene expression, epigenetic] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] GO:0071169 [establishment of protein localization to chromatin] GO:1901837 [negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter]
