Tissue expression of ITPKA - Mouse brain

MOUSE BRAIN TISSUE

Gene description	Inositol-trisphosphate 3-kinase A
Human tissue RNA category	Tissue enhanced (cerebral cortex, duodenum, small intestine).
Mouse gene	ENSMUSG00000027296 (version 83)
Annotation summary	Staining observed in subsets of astrocytes, most abundant in hippocampus and subiculum. End feet positivity was seen as accentuation to blood vessel walls.
Positive cells and structures	Soma and endfeet in astrocytes.
Reliability	Approved

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Human caudate

Hypothalamus

Subiculum

Hippocampus

	Protein
	Relative fluorescence intensity
Mouse brain region	255 0
olfactory bulb, forebrain
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)	N/A
basal forebrain, forebrain
Dorsal tenia tecta (dtt)
Caudate putamen (cpu)
Accumbens nucleus, core (acbc)
Accumbens nucleus, shell (acbsh)
Island of Calleja (icj)
Ventral pallidum (vp)
Medial septum (ms)
Nucleus of the vertical limb of the diagonal band (vdb)
Lateral septum (ls)
Nucleus of the horizontal limb of the diagonal band (hdb)	N/A
Globus pallidus (gp)
cerebral cortex, forebrain
Frontal association cortex (fra)	N/A
Motor cortex (m)	N/A
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
hippocampus, forebrain
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
circumventricular organs, forebrain
Subfornical organ (sfo)	N/A
amygdala, forebrain
Nucleus of the lateral olfactory tract (lot)	N/A
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
hypothalamus, interbrain
Dorsal tuberomammillary nucleus (dtm)	N/A
Mammillary nucleus (mn)
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)	N/A
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm)	N/A
Lateral preoptic area (lpo)	N/A
Medial preoptic area (mpo)	N/A
Suprachiasmatic nucleus (sch)	N/A
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Arcuate nucleus (arc)
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
circumventricular organs, interbrain
Subcommissural organ (sco)	N/A
Median eminence (me)
thalamus, interbrain
Medial geniculate nucleus (mg)
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
Stria terminalis (st)
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)	N/A
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl)	N/A
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)
midbrain motor, midbrain
Substantia nigra, reticular (snr)
Periaquaductal grey (pag)
Interpeduncular nucleus (ip)
Mesencephalic retic form (mrt)
Red nucleus (r)
Oculomotor nucleus (3n)	N/A
Mesencephalic trigeminal nucleus (me5)	N/A
Ventral tegmental area (vta)
midbrain behavioral, midbrain
Substantia nigra, compact (snc)
Dorsal raphe nucleus (dr)
Median raphe nucleus (mnr)
midbrain sensory, midbrain
Superior colliculi (sc)
External cortical inferior colliculli (ecic)
cerebellum, hindbrain
Vestibulocerebellar nucleus (vecb)	N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
circumventricular organs, hindbrain
Medulla (ap)	N/A
pons, hindbrain
Barrington's nucleus (bar)	N/A
Koelliker-fuse nucleus (kf)	N/A
Motor tregiminal nucleus (5n)
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)
Pontine nucleus (pn)
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)	N/A
medulla, hindbrain
Nucleus of the solitary tract (sol)
Raphe magnus nucleus (rmg)
Cochlear nucleus (cn)
Lateral paragigantocellular nucleus (lpg)
Raphe pallidus nucleus (rpa)
Facial nucleus (7n)
Hypoglossal nucleus (12n)	N/A
Ambiguus nucleus (amb)
External cuneate nucleus (ecu)	N/A
Inferior olivary nucleus (io)	N/A
Raphe obscures nucleus (rob)	N/A
Dorsal motor nucleus of vagus (10n)	N/A

Antibodies in assay
HPA040454