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PRKACB

GENERAL INFORMATION

Gene name

 PRKACB

Gene description

 Protein kinase, cAMP-dependent, catalytic, beta

Protein class

 Enzymes
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 17
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Caution, Splice and/or transcript discrepancy exists.

Reliability score

 Approved based on 2 antibodies.
HPA029754 , CAB010363
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PRKACB (HGNC Symbol)

Synonyms

 PKACb

Description

 Protein kinase, cAMP-dependent, catalytic, beta (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014]

Chromosome

 1

Cytoband

 p31.1

Chromosome location (bp)

 84078062 - 84238498

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000142875 (version 83.38)

Entrez gene

 5567

UniProt

 P22694 (UniProt - Evidence at protein level)

neXtProt

 NX_P22694

Antibodypedia

 PRKACB antibodies

PROTEIN BROWSER
«
PRKACB-001
PRKACB-002
PRKACB-003
PRKACB-004
PRKACB-005
PRKACB-007
PRKACB-008
PRKACB-009
PRKACB-010
PRKACB-011
PRKACB-012
PRKACB-013
PRKACB-201
PRKACB-202
PRKACB-203
PRKACB-204
PRKACB-205
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PRKACB-001
ENSP00000359723
ENST00000370689
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
B2RB89 [Target identity:100%; Query identity:100%]
Protein kinase, cAMP-dependent, catalytic, beta, isoform CRA_a; cAMP-dependent protein kinase catalytic subunit beta isoform 2; cDNA, FLJ95374, Homo sapiens protein kinase, cAMP-dependent, catalytic, beta(PRKACB), transcript variant 2, mRNA
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 351 aa
40.6 kDa 		No 0
PRKACB-002
ENSP00000359722
ENST00000370688
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 257 aa
29.7 kDa 		No 0
PRKACB-003
ENSP00000359714
ENST00000370680
B1APG3 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 264 aa
30.5 kDa 		No 0
PRKACB-004
ENSP00000359719
ENST00000370685
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0001843 [neural tube closure]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050796 [regulation of insulin secretion]
GO:0051447 [negative regulation of meiotic cell cycle]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0070613 [regulation of protein processing]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097338 [response to clozapine]
GO:0097546 [ciliary base]
GO:1901621 [negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning]
Show all
 398 aa
46.2 kDa 		No 0
PRKACB-005
ENSP00000378315
ENST00000394839
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 321 aa
37 kDa 		No 0
PRKACB-007
ENSP00000401252
ENST00000446538
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 358 aa
41.4 kDa 		No 0
PRKACB-008
ENSP00000359718
ENST00000370684
B1APF9 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 245 aa
28.5 kDa 		No 0
PRKACB-009
ENSP00000390906
ENST00000436133
B1APF7 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 186 aa
21.6 kDa 		No 0
PRKACB-010
ENSP00000392275
ENST00000432111
B1APF8 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 214 aa
24.9 kDa 		No 0
PRKACB-011
ENSP00000393654
ENST00000450730
B1APG0 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 206 aa
23.9 kDa 		No 0
PRKACB-012
ENSP00000397175
ENST00000413538
B1APG2 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 209 aa
24.3 kDa 		No 0
PRKACB-013
ENSP00000399326
ENST00000417530
B1APG1 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 197 aa
23.1 kDa 		No 0
PRKACB-201
ENSP00000359716
ENST00000370682
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 355 aa
41 kDa 		No 0
PRKACB-202
ENSP00000378314
ENST00000394838
A0A0A0MS54 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 357 aa
41.3 kDa 		No 0
PRKACB-203
ENSP00000479339
ENST00000610457
A0A087WVC4 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 338 aa
39.2 kDa 		No 0
PRKACB-204
ENSP00000481980
ENST00000610703
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 339 aa
39.5 kDa 		No 0
PRKACB-205
ENSP00000479722
ENST00000614872
P22694 [Direct mapping]
cAMP-dependent protein kinase catalytic subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0003091 [renal water homeostasis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004691 [cAMP-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005952 [cAMP-dependent protein kinase complex]
GO:0005975 [carbohydrate metabolic process]
GO:0006006 [glucose metabolic process]
GO:0006094 [gluconeogenesis]
GO:0006112 [energy reserve metabolic process]
GO:0006468 [protein phosphorylation]
GO:0006833 [water transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway]
GO:0007202 [activation of phospholipase C activity]
GO:0007268 [synaptic transmission]
GO:0007596 [blood coagulation]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0019433 [triglyceride catabolic process]
GO:0031625 [ubiquitin protein ligase binding]
GO:0034199 [activation of protein kinase A activity]
GO:0035556 [intracellular signal transduction]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050796 [regulation of insulin secretion]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097546 [ciliary base]
Show all
 357 aa
41.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.