Fields »
ABOUT
HELP
BLOG
OTUD6B

GENERAL INFORMATION

Gene name

 OTUD6B

Gene description

 OTU domain containing 6B

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 3 antibodies.
HPA024046 , HPA024503 , HPA024772
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 OTUD6B (HGNC Symbol)

Synonyms

 CGI-77, DUBA5

Description

 OTU domain containing 6B (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells. [provided by RefSeq, Nov 2013]

Chromosome

 8

Cytoband

 q21.3

Chromosome location (bp)

 91070196 - 91087095

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000155100 (version 83.38)

Entrez gene

 51633

UniProt

 Q8N6M0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N6M0

Antibodypedia

 OTUD6B antibodies

PROTEIN BROWSER
OTUD6B-001
OTUD6B-004
OTUD6B-201
OTUD6B-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
OTUD6B-001
ENSP00000285420
ENST00000285420
A0A087X0W9 [Direct mapping]
OTU domain containing 6B, isoform CRA_b; OTU domain-containing protein 6B
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
 323 aa
37.3 kDa 		No 0
OTUD6B-004
ENSP00000384190
ENST00000404789
Q8N6M0 [Direct mapping]
OTU domain-containing protein 6B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008234 [cysteine-type peptidase activity]
Show all
 293 aa
33.8 kDa 		No 0
OTUD6B-201
ENSP00000481196
ENST00000615618
Q8N6M0 [Direct mapping]
OTU domain-containing protein 6B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008234 [cysteine-type peptidase activity]
Show all
 192 aa
21.8 kDa 		No 0
OTUD6B-202
ENSP00000483706
ENST00000617869
A0A087X0W9 [Direct mapping]
OTU domain containing 6B, isoform CRA_b; OTU domain-containing protein 6B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 323 aa
37.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.