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SFMBT1

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GENERAL INFORMATION

Gene name

 SFMBT1

Gene description

 Scm-like with four mbt domains 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the nucleoplasm.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (validated)

DATA RELIABILITY

Reliability score

 Validated based on 2 antibodies.
HPA036152 , HPA064564
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the nucleoplasm.

Main location

 Nucleoplasm (validated)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA036152 A-431 Nucleoplasm
HPA036152 U-2 OS No staining    
HPA036152 U-251 MG Nucleoplasm
HPA064564 SiHa Nucleoplasm
HPA064564 U-2 OS Nucleoplasm

GENE INFORMATION

Gene name

 SFMBT1 (HGNC Symbol)

Synonyms

 DKFZp434L243, RU1, SFMBT

Description

 Scm-like with four mbt domains 1 (HGNC Symbol)

Entrez gene summary

 This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]

Chromosome

 3

Cytoband

 p21.1

Chromosome location (bp)

 52903572 - 53046750

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163935 (version 83.38)

Entrez gene

 51460

UniProt

 Q9UHJ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UHJ3

Antibodypedia

 SFMBT1 antibodies

PROTEIN BROWSER
SFMBT1-001
SFMBT1-004
SFMBT1-005
SFMBT1-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SFMBT1-001
ENSP00000378235
ENST00000394752
Q9UHJ3 [Direct mapping]
Scm-like with four MBT domains protein 1
A0A024R338 [Target identity:100%; Query identity:100%]
Scm-like with four mbt domains 1, isoform CRA_b
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007283 [spermatogenesis]
GO:0016568 [chromatin modification]
GO:0030154 [cell differentiation]
GO:0042393 [histone binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0048635 [negative regulation of muscle organ development]
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 866 aa
98.1 kDa 		No 0
SFMBT1-004
ENSP00000418950
ENST00000483069
C9IZZ5 [Direct mapping]
Scm-like with four MBT domains protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
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 94 aa
10.5 kDa 		No 0
SFMBT1-005
ENSP00000418860
ENST00000482396
C9IY64 [Direct mapping]
Scm-like with four MBT domains protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
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 121 aa
13.8 kDa 		No 0
SFMBT1-008
ENSP00000419215
ENST00000497586
C9JWI3 [Direct mapping]
Scm-like with four MBT domains protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 50 aa
5.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.