Fields »
ABOUT
HELP
BLOG
SFMBT1

GENERAL INFORMATION

Gene name

 SFMBT1

Gene description

 Scm-like with four mbt domains 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (parathyroid gland, testis)
GTEx:Tissue enriched (testis)
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a majority of tissues, most abundant in gastrointestinal tract and testis.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA036152 , HPA036153
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (parathyroid gland, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SFMBT1 (HGNC Symbol)

Synonyms

 DKFZp434L243, RU1, SFMBT

Description

 Scm-like with four mbt domains 1 (HGNC Symbol)

Entrez gene summary

 This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]

Chromosome

 3

Cytoband

 p21.1

Chromosome location (bp)

 52903572 - 53046750

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163935 (version 83.38)

Entrez gene

 51460

UniProt

 Q9UHJ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UHJ3

Antibodypedia

 SFMBT1 antibodies

PROTEIN BROWSER
SFMBT1-001
SFMBT1-004
SFMBT1-005
SFMBT1-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SFMBT1-001
ENSP00000378235
ENST00000394752
Q9UHJ3 [Direct mapping]
Scm-like with four MBT domains protein 1
A0A024R338 [Target identity:100%; Query identity:100%]
Scm-like with four mbt domains 1, isoform CRA_b
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007283 [spermatogenesis]
GO:0016568 [chromatin modification]
GO:0030154 [cell differentiation]
GO:0042393 [histone binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0048635 [negative regulation of muscle organ development]
Show all
 866 aa
98.1 kDa 		No 0
SFMBT1-004
ENSP00000418950
ENST00000483069
C9IZZ5 [Direct mapping]
Scm-like with four MBT domains protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 94 aa
10.5 kDa 		No 0
SFMBT1-005
ENSP00000418860
ENST00000482396
C9IY64 [Direct mapping]
Scm-like with four MBT domains protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 121 aa
13.8 kDa 		No 0
SFMBT1-008
ENSP00000419215
ENST00000497586
C9JWI3 [Direct mapping]
Scm-like with four MBT domains protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 50 aa
5.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.