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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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NOC2L
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

NOC2L

Gene description

NOC2-like nucleolar associated transcriptional repressor

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nucleolar and cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA044258
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

NOC2L (HGNC Symbol)

Synonyms

DKFZP564C186, NET15, NET7, NIR, PPP1R112

Description

NOC2-like nucleolar associated transcriptional repressor (HGNC Symbol)

Entrez gene summary

Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008]

Chromosome

1

Cytoband

p36.33

Chromosome location (bp)

944204 - 959309

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188976 (version 83.38)

Entrez gene

26155

UniProt

Q9Y3T9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3T9

Antibodypedia

NOC2L antibodies

PROTEIN BROWSER

NOC2L-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOC2L-001
ENSP00000317992
ENST00000327044
Q9Y3T9 [Direct mapping]
Nucleolar complex protein 2 homolog
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   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003682 [chromatin binding]
GO:0003714 [transcription corepressor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0006915 [apoptotic process]
GO:0031491 [nucleosome binding]
GO:0031497 [chromatin assembly]
GO:0032066 [nucleolus to nucleoplasm transport]
GO:0034644 [cellular response to UV]
GO:0035067 [negative regulation of histone acetylation]
GO:0042393 [histone binding]
GO:0044822 [poly(A) RNA binding]
GO:0070491 [repressing transcription factor binding]
GO:2001243 [negative regulation of intrinsic apoptotic signaling pathway]
Show all
749 aa
84.9 kDa
No 0

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