The human protein atlas blog


Plenary lecture at Clinical Proteomics, Postgenome Medicine, Moscow, Russia.

2017-10-27
Conference Human Protein Atlas Omics Pathology Precision medicine Tissue Atlas

Dr Cecilia Lindskog, presents a plenary lecture on October 31 entitled "The Human Protein Atlas - implications for human biology and precision medicine" on the Clinical Proteomics, Postgenome Medicine conference in Moscow, Russia. Dr Lindskog is highlighted as one of the key speakers of the conference.

The 300+ international participants at the conference include medical advisors, scientists and business representatives to bridge translation of research findings to clinical use. The conference opens the fields of "omics" science (genomics, transcriptomics, proteomics, metabolomics) to clinical practioners...Read more


Human Protein Atlas presentations at the 16th HUPO World Congress

2017-09-14
Affinity proteomics Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Immunohistochemistry Sub-cellular structures Tissue Atlas

Next week on the 17th to 21th of September, the human proteome organization (HUPO), is hosting the 16th HUPO World Congress in Dublin, Ireland. Several Human Protein Atlas-associated researchers will attend the meeting and represent the project in various sessions, including plenary and invited lectures, oral presentations and poster sessions.

HUPO is an international scientific organization representing and promoting proteomics through international cooperation and collaborations by fostering the development of new technologies, techniques and training...Read more


Crystallins are proteins expressed in the human eye with a long life

2017-07-22
Eye Image of the week Immunocytochemistry Immunohistochemistry Lens proteins Pathology tissue Tissue Atlas

The beta-crystallin B2 protein, encoded by the CRYBB2 gene, is a very important structural component of the human eye lens. Immunohistochemical staining of CRYBB2 protein shows specific expression in the lens.

Previously we have highlighted proteins expressed in the human neural retina. This week's article emphasizes the cellular structure and molecular dynamics of the lens.

The main function of the lens is to focus light on the retina. The passage of light through the cornea, lens and vitreous all the way to the retinal layer of the eye is only possible due to transparency of the tissue. Although the lens is very protein-rich, light absorption and light scattering in the lens is minimal.

The lens comprises non-diving lens cells which are mainly composed of ordered proteins called crystallins...Read more


Expression of genes in mammary glands

2017-06-12
Immunohistochemistry tissue Tissue Atlas

In this week’s post, we will highlight proteins specifically expressed in a tissue with extensive plasticity - the female mammary glands. The evolutionary origin of mammary and milk gland-like structures is believed to date all the way back to 300 million years ago, and glandular secretory apocrine-like units in the skin of synapsids, an ancestor to mammals.

The mammary gland develops from the epidermis and is mainly composed of branched columnar and cuboidal epithelial cells that form distinct lobes...Read more


Pituitary gland links the nervous and the endocrine systems in the human body

2017-05-05
Brain Image of the week Immunohistochemistry Pituitary gland tissue Tissue Atlas

The pituitary gland plays a crucial role in human physiology, and together with the hypothalamus this highly conserved and elegant system form a link between the nervous and endocrine system, by controlling the functions of the thyroid, adrenal glands, and the gonads, and also regulating growth, lactation, and water preservation.

This gland, also called hypophysis, consists of two separate lobes with dual embryonic origin; the anterior (adeno) pituitary gland originates from the oral cavity, and the posterior (neural) pituitary gland develops from the neural plate...Read more


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