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Term
Gene name

Class

Subclass

Chromosome

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In atlas

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Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

Score

Score

Antibodies

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ABCF2
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    TISSUE

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    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ABCF2

Gene description

ATP-binding cassette, sub-family F (GCN20), member 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Widely distributed cytoplasmic staining.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 4 antibodies.
HPA020091 , HPA021815 , HPA030388 , CAB020682
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ABCF2 (HGNC Symbol)

Synonyms

ABC28, EST133090, HUSSY-18, M-ABC1

Description

ATP-binding cassette, sub-family F (GCN20), member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding casette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Jul 2013]

Chromosome

7

Cytoband

q36.1

Chromosome location (bp)

151207837 - 151227230

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000033050 (version 83.38)

Entrez gene

10061

UniProt

Q9UG63 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UG63

Antibodypedia

ABCF2 antibodies

PROTEIN BROWSER

ABCF2-001
ABCF2-003
ABCF2-004
ABCF2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCF2-001
ENSP00000287844
ENST00000287844
Q9UG63 [Direct mapping]
ATP-binding cassette sub-family F member 2
A0A090N7X1 [Target identity:100%; Query identity:100%]
ATP-binding cassette, sub-family F (GCN20), member 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005524 [ATP binding]
GO:0005740 [mitochondrial envelope]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016887 [ATPase activity]
GO:0043190 [ATP-binding cassette (ABC) transporter complex]
Show all
623 aa
71.3 kDa
No 0
ABCF2-003
ENSP00000222388
ENST00000222388
Q9UG63 [Direct mapping]
ATP-binding cassette sub-family F member 2
A0A090N7Y2 [Target identity:100%; Query identity:100%]
ATP-binding cassette, sub-family F (GCN20), member 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005524 [ATP binding]
GO:0005739 [mitochondrion]
GO:0005740 [mitochondrial envelope]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016887 [ATPase activity]
GO:0043190 [ATP-binding cassette (ABC) transporter complex]
Show all
634 aa
72.4 kDa
No 0
ABCF2-004
ENSP00000395785
ENST00000441774
C9JHK9 [Direct mapping]
ATP-binding cassette sub-family F member 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
240 aa
26.9 kDa
No 0
ABCF2-006
ENSP00000419720
ENST00000468073
C9JZV3 [Direct mapping]
ATP-binding cassette sub-family F member 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
288 aa
32.6 kDa
No 0

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