Tissue expression of ABCF2 - Summary - The Human Protein Atlas

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ABCF2

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ABCF2
Gene description	ATP-binding cassette, sub-family F (GCN20), member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Widely distributed cytoplasmic staining.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 4 antibodies. HPA020091 , HPA021815 , HPA030388 , CAB020682
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ABCF2 (HGNC Symbol)
Synonyms	ABC28, EST133090, HUSSY-18, M-ABC1
Description	ATP-binding cassette, sub-family F (GCN20), member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding casette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Jul 2013]
Chromosome	7
Cytoband	q36.1
Chromosome location (bp)	151207837 - 151227230
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000033050 (version 83.38)
Entrez gene	10061
UniProt	Q9UG63 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UG63
Antibodypedia	ABCF2 antibodies

PROTEIN BROWSER

ABCF2-001	ABCF2-003	ABCF2-004	ABCF2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABCF2-001 ENSP00000287844 ENST00000287844	Q9UG63 [Direct mapping] ATP-binding cassette sub-family F member 2 A0A090N7X1 [Target identity:100%; Query identity:100%] ATP-binding cassette, sub-family F (GCN20), member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005524 [ATP binding] GO:0005740 [mitochondrial envelope] GO:0006810 [transport] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016887 [ATPase activity] GO:0043190 [ATP-binding cassette (ABC) transporter complex] Show all	623 aa 71.3 kDa	No	0
ABCF2-003 ENSP00000222388 ENST00000222388	Q9UG63 [Direct mapping] ATP-binding cassette sub-family F member 2 A0A090N7Y2 [Target identity:100%; Query identity:100%] ATP-binding cassette, sub-family F (GCN20), member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005524 [ATP binding] GO:0005739 [mitochondrion] GO:0005740 [mitochondrial envelope] GO:0006810 [transport] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016887 [ATPase activity] GO:0043190 [ATP-binding cassette (ABC) transporter complex] Show all	634 aa 72.4 kDa	No	0
ABCF2-004 ENSP00000395785 ENST00000441774	C9JHK9 [Direct mapping] ATP-binding cassette sub-family F member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] Show all	240 aa 26.9 kDa	No	0
ABCF2-006 ENSP00000419720 ENST00000468073	C9JZV3 [Direct mapping] ATP-binding cassette sub-family F member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] Show all	288 aa 32.6 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.