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Term
Gene name

Class

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Chromosome

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In atlas

Reliability

Reliability

Reliability

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Method

Validation

Method

Validation

Method

Validation

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Searches

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Specificity

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Cancer

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Detectable

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Detectable

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GORASP2
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    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

GORASP2

Gene description

Golgi reassembly stacking protein 2, 55kDa

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and cell membranous expression in several tissues, mainly in the gastrointestinal tract.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Paired antibodies with high similarity supports the protein expression.

Reliability score

Supported based on 2 antibodies.
HPA035274 , HPA035275
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

GORASP2 (HGNC Symbol)

Synonyms

GOLPH6, GRASP55, GRS2

Description

Golgi reassembly stacking protein 2, 55kDa (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

170928464 - 170967129

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115806 (version 83.38)

Entrez gene

26003

UniProt

Q9H8Y8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H8Y8

Antibodypedia

GORASP2 antibodies

PROTEIN BROWSER

GORASP2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GORASP2-001
ENSP00000234160
ENST00000234160
Q9H8Y8 [Direct mapping]
Golgi reassembly-stacking protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0000278 [mitotic cell cycle]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0006996 [organelle organization]
GO:0016020 [membrane]
Show all
452 aa
47.1 kDa
No 0

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