Cell atlas - SNRNP25 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SNRNP25

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS CELL CYCLE

GENE/PROTEIN

Antibody validation

Dictionary
	Cytokinetic bridge
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Microtubules
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	SNRNP25
Gene description	Small nuclear ribonucleoprotein 25kDa (U11/U12)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol & cytokinetic bridge.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Cytokinetic bridge (approved), Cytosol (approved)
Single-cell variation	Single-cell variation in protein expression observed.
Cell cycle dependency	Cell cycle dependent expression determined by biological definition

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA041183
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol & cytokinetic bridge.

Main location

Nucleoplasm (supported)

Additional location

Cytokinetic bridge (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041183	A-431	Nucleoplasm
	HPA041183	A-431	Cytosol
	HPA041183	U-2 OS	Nucleoplasm
			Cytokinetic bridge	Intensity	Intensity
			Cytosol
	HPA041183	U-251 MG	Nucleoplasm
	HPA041183	U-251 MG	Cytosol

CELL CYCLE
Summary	Expression has cell cycle dependency according to biological definition
Intensity variation	Cytokinetic bridge

GENE INFORMATION
Gene name	SNRNP25 (HGNC Symbol)
Synonyms	C16orf33
Description	Small nuclear ribonucleoprotein 25kDa (U11/U12) (HGNC Symbol)
Entrez gene summary	Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome. [provided by RefSeq, Apr 2010]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	53010 - 57669
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000161981 (version 83.38)
Entrez gene	79622
UniProt	Q9BV90 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BV90
Antibodypedia	SNRNP25 antibodies

PROTEIN BROWSER

SNRNP25-001	SNRNP25-006	SNRNP25-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNRNP25-001 ENSP00000293861 ENST00000293861	Q4TT61 [Direct mapping] Chromosome 16 open reading frame 33; U11/U12 small nuclear ribonucleoprotein 25 kDa protein Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0045171 [intercellular bridge] Show all	123 aa 14.3 kDa	No	0
SNRNP25-006 ENSP00000391289 ENST00000417493	B8ZZ06 [Direct mapping] Chromosome 16 open reading frame 33; U11/U12 small nuclear ribonucleoprotein 25 kDa protein Show all	Predicted intracellular proteins Show all		96 aa 11.1 kDa	No	0
SNRNP25-201 ENSP00000372482 ENST00000383018	Q9BV90 [Direct mapping] U11/U12 small nuclear ribonucleoprotein 25 kDa protein Show all	Predicted intracellular proteins Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005689 [U12-type spliceosomal complex] GO:0005737 [cytoplasm] GO:0008380 [RNA splicing] GO:0010467 [gene expression] GO:0045171 [intercellular bridge] Show all	132 aa 15.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.