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551 GENES FOUND

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Pathology

 

 

 

 

 

 

Subcellular location

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RNA tissue category

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POLBPolymerase (DNA directed), betaEnzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
VesiclesExpressed in all
POLEPolymerase (DNA directed), epsilon, catalytic subunitCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Plasma membrane		Expressed in all
POLE2Polymerase (DNA directed), epsilon 2, accessory subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleoplasm
Nuclear bodies
Vesicles		Mixed
POLE3Polymerase (DNA directed), epsilon 3, accessory subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Nucleoli		Expressed in all
POLE4Polymerase (DNA-directed), epsilon 4, accessory subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Cytosol		Expressed in all
PPARAPeroxisome proliferator-activated receptor alphaFDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors
NucleusExpressed in all
PPARDPeroxisome proliferator-activated receptor deltaFDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors
Expressed in all
PPARGPeroxisome proliferator-activated receptor gammaCancer-related genes
Disease related genes
FDA approved drug targets
Nuclear receptors
Plasma proteins
Predicted intracellular proteins
Transcription factors
Nucleus
Vesicles		Tissue enhanced
PPP3R2Protein phosphatase 3, regulatory subunit B, betaFDA approved drug targets
Predicted intracellular proteins
Plasma membrane
Cytosol		Tissue enriched
PRDX5Peroxiredoxin 5Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Mitochondria
Cytosol		Expressed in all
PRKAA1Protein kinase, AMP-activated, alpha 1 catalytic subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nuclear specklesExpressed in all
PRKAB1Protein kinase, AMP-activated, beta 1 non-catalytic subunitFDA approved drug targets
Predicted intracellular proteins
Nucleoplasm
Cytosol		Expressed in all
PROCProtein C (inactivator of coagulation factors Va and VIIIa)Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Tissue enriched
PROS1Protein S (alpha)Candidate cardiovascular disease genes
Disease related genes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Tissue enhanced
PSMB1Proteasome subunit beta 1Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleusExpressed in all
PSMB10Proteasome subunit beta 10Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Vesicles
Cytosol		Expressed in all
PSMB2Proteasome subunit beta 2Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
PSMB5Proteasome subunit beta 5Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Centrosome		Expressed in all
PSMB8Proteasome subunit beta 8Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Vesicles
Cytokinetic bridge		Mixed
PSMB9Proteasome subunit beta 9Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
CytosolMixed
PSMD1Proteasome 26S subunit, non-ATPase 1FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Nucleoplasm
Actin filaments		Expressed in all
PSMD2Proteasome 26S subunit, non-ATPase 2FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Expressed in all
PTGER3Prostaglandin E receptor 3 (subtype EP3)FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Group enriched
PTGER4Prostaglandin E receptor 4 (subtype EP4)FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Expressed in all
PTGISProstaglandin I2 (prostacyclin) synthaseDisease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Mixed
PTGS1Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)Cancer-related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted secreted proteins
Golgi apparatus
Vesicles		Tissue enhanced
PTGS2Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)Cancer-related genes
Enzymes
FDA approved drug targets
Predicted secreted proteins
Endoplasmic reticulumTissue enhanced
PTH2RParathyroid hormone 2 receptorFDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Mixed
QPRTQuinolinate phosphoribosyltransferaseEnzymes
FDA approved drug targets
Plasma proteins
Predicted secreted proteins
Expressed in all
RAF1Raf-1 proto-oncogene, serine/threonine kinaseCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
RAS pathway related proteins
Nuclear specklesExpressed in all
RAMP1Receptor (G protein-coupled) activity modifying protein 1FDA approved drug targets
Predicted membrane proteins
Nucleoplasm
Nuclear membrane		Tissue enhanced
RAMP2Receptor (G protein-coupled) activity modifying protein 2FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
VesiclesMixed
RARARetinoic acid receptor, alphaCancer-related genes
Disease related genes
FDA approved drug targets
Nuclear receptors
Plasma proteins
Predicted intracellular proteins
Transcription factors
Nucleus
Cytosol		Expressed in all
RARBRetinoic acid receptor, betaCancer-related genes
Disease related genes
FDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors
NucleoplasmMixed
RARGRetinoic acid receptor, gammaCancer-related genes
FDA approved drug targets
Nuclear receptors
Plasma proteins
Predicted intracellular proteins
Transcription factors
NucleoplasmTissue enhanced
RENReninCandidate cardiovascular disease genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted secreted proteins
Tissue enhanced
RETRet proto-oncogeneCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins
Vesicles
Plasma membrane
Cytosol		Tissue enriched
RFKRiboflavin kinaseEnzymes
FDA approved drug targets
Predicted intracellular proteins
Golgi apparatusExpressed in all
RPL3Ribosomal protein L3FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Ribosomal proteins
Nucleoli
Cytosol		Expressed in all
RRM1Ribonucleotide reductase M1Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
RRM2Ribonucleotide reductase M2Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
CytosolMixed
RRM2BRibonucleotide reductase M2 B (TP53 inducible)Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted membrane proteins
Nucleoplasm
Cytosol		Expressed in all
RXRARetinoid X receptor, alphaCancer-related genes
FDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors
Nucleus
Golgi apparatus		Mixed
RXRBRetinoid X receptor, betaCancer-related genes
FDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors
NucleusMixed
RXRGRetinoid X receptor, gammaCancer-related genes
FDA approved drug targets
Nuclear receptors
Plasma proteins
Predicted intracellular proteins
Transcription factors
Tissue enhanced
RYR1Ryanodine receptor 1 (skeletal)Disease related genes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Transporters
Golgi apparatus
Vesicles
Cytosol		Tissue enriched
S1PR5Sphingosine-1-phosphate receptor 5FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Tissue enhanced
SCN11ASodium channel, voltage gated, type XI alpha subunitDisease related genes
FDA approved drug targets
Predicted membrane proteins
Transporters
Voltage-gated ion channels
Tissue enhanced
SCN1ASodium channel, voltage gated, type I alpha subunitDisease related genes
FDA approved drug targets
Predicted membrane proteins
Transporters
Voltage-gated ion channels
Nucleoplasm
Nuclear bodies
Plasma membrane		Tissue enhanced
SCN2ASodium channel, voltage gated, type II alpha subunitDisease related genes
FDA approved drug targets
Predicted membrane proteins
Transporters
Voltage-gated ion channels
Tissue enriched

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.