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250 GENES FOUND

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Gene

 

 

Gene description

x

 

 

Protein class

x

 

 

 

 

Tissue

Cell

Pathology

 

 

 

 

 

 

Subcellular location

x

 

 

RNA tissue category

x

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
POLE3Polymerase (DNA directed), epsilon 3, accessory subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Nucleoli		Expressed in all
POLE4Polymerase (DNA-directed), epsilon 4, accessory subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Cytosol		Expressed in all
PRDX5Peroxiredoxin 5Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Mitochondria
Cytosol		Expressed in all
PRKAA1Protein kinase, AMP-activated, alpha 1 catalytic subunitEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nuclear specklesExpressed in all
PROCProtein C (inactivator of coagulation factors Va and VIIIa)Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Tissue enriched
PSMB1Proteasome subunit beta 1Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleusExpressed in all
PSMB10Proteasome subunit beta 10Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Vesicles
Cytosol		Expressed in all
PSMB2Proteasome subunit beta 2Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
PSMB5Proteasome subunit beta 5Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Centrosome		Expressed in all
PSMB8Proteasome subunit beta 8Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Vesicles
Cytokinetic bridge		Mixed
PSMB9Proteasome subunit beta 9Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
CytosolMixed
PTGISProstaglandin I2 (prostacyclin) synthaseDisease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Mixed
PTGS1Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)Cancer-related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted secreted proteins
Golgi apparatus
Vesicles		Tissue enhanced
PTGS2Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)Cancer-related genes
Enzymes
FDA approved drug targets
Predicted secreted proteins
Endoplasmic reticulumTissue enhanced
QPRTQuinolinate phosphoribosyltransferaseEnzymes
FDA approved drug targets
Plasma proteins
Predicted secreted proteins
Expressed in all
RAF1Raf-1 proto-oncogene, serine/threonine kinaseCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
RAS pathway related proteins
Nuclear specklesExpressed in all
RENReninCandidate cardiovascular disease genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted secreted proteins
Tissue enhanced
RETRet proto-oncogeneCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins
Vesicles
Plasma membrane
Cytosol		Tissue enriched
RFKRiboflavin kinaseEnzymes
FDA approved drug targets
Predicted intracellular proteins
Golgi apparatusExpressed in all
RRM1Ribonucleotide reductase M1Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
RRM2Ribonucleotide reductase M2Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
CytosolMixed
RRM2BRibonucleotide reductase M2 B (TP53 inducible)Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted membrane proteins
Nucleoplasm
Cytosol		Expressed in all
SHMT1Serine hydroxymethyltransferase 1 (soluble)Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Cytosol		Expressed in all
SISucrase-isomaltase (alpha-glucosidase)Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Group enriched
SMOXSpermine oxidaseEnzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleoplasm
Nuclear membrane
Vesicles		Tissue enhanced
SMSSpermine synthaseDisease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Nuclear bodies
Cytosol		Expressed in all
SOAT1Sterol O-acyltransferase 1Enzymes
FDA approved drug targets
Predicted membrane proteins
Endoplasmic reticulumTissue enhanced
SQLESqualene epoxidaseEnzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted membrane proteins
Vesicles
Cytosol		Mixed
SRCSRC proto-oncogene, non-receptor tyrosine kinaseCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Plasma membrane
Cytosol		Mixed
SRD5A1Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)Cancer-related genes
Enzymes
FDA approved drug targets
Predicted membrane proteins
Mixed
SRD5A2Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)Cancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted membrane proteins
Group enriched
TBXAS1Thromboxane A synthase 1 (platelet)Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
VesiclesMixed
TEKTEK tyrosine kinase, endothelialCancer-related genes
CD markers
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins
RAS pathway related proteins
Plasma membrane
Microtubule organizing center		Tissue enhanced
THTyrosine hydroxylaseDisease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Tissue enriched
TOP1Topoisomerase (DNA) ICancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Nucleoli fibrillar center		Expressed in all
TOP1MTTopoisomerase (DNA) I, mitochondrialEnzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted secreted proteins
MitochondriaExpressed in all
TOP2ATopoisomerase (DNA) II alphaCancer-related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Nucleoli		Tissue enhanced
TOP2BTopoisomerase (DNA) II betaEnzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleusExpressed in all
TPH1Tryptophan hydroxylase 1Enzymes
FDA approved drug targets
Predicted intracellular proteins
CytosolGroup enriched
TPK1Thiamin pyrophosphokinase 1Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
VesiclesMixed
TPMTThiopurine S-methyltransferaseDisease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Expressed in all
TPOThyroid peroxidaseDisease related genes
Enzymes
FDA approved drug targets
Predicted membrane proteins
Predicted secreted proteins
Tissue enriched
TXNRD1Thioredoxin reductase 1Cancer-related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleusExpressed in all
TYMSThymidylate synthetaseCancer-related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Mixed
TYRTyrosinaseDisease related genes
Enzymes
FDA approved drug targets
Predicted membrane proteins
VesiclesTissue enriched
UGCGUDP-glucose ceramide glucosyltransferaseEnzymes
FDA approved drug targets
Predicted membrane proteins
Transporters
Expressed in all
VKORC1Vitamin K epoxide reductase complex, subunit 1Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Expressed in all
VKORC1L1Vitamin K epoxide reductase complex, subunit 1-like 1Enzymes
FDA approved drug targets
Predicted membrane proteins
Endoplasmic reticulumExpressed in all
XDHXanthine dehydrogenaseDisease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
NucleusTissue enhanced
YES1YES proto-oncogene 1, Src family tyrosine kinaseEnzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Plasma membrane
Cytosol		Expressed in all

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.