Search: protein_class:FDA approved drug targets AND protein_class:G-protein coupled receptors - The Human Protein Atlas

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95 GENES FOUND

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Gene

Gene description	x

Protein class	x

Tissue

Cell

Pathology

Subcellular location	x

RNA tissue category	x

Hydroxycarboxylic acid receptor 3

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Hypocretin (orexin) receptor 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Hypocretin (orexin) receptor 2

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

HRH1

Histamine receptor H1

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Plasma membrane
Cytosol

HRH2

Histamine receptor H2

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

HRH3

Histamine receptor H3

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Plasma membrane

Tissue enhanced

5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Tissue enhanced

HTR6

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

HTR7

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
RAS pathway related proteins

Nuclear speckles
Plasma membrane
Cytosol

Luteinizing hormone/choriogonadotropin receptor

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

MC2R

Melanocortin 2 receptor (adrenocorticotropic hormone)

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enriched

Melatonin receptor 1A

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

Melatonin receptor 1B

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Tissue enhanced

Neurotensin receptor 2

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

Opioid receptor, delta 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Opioid receptor, kappa 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Opioid receptor, mu 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

OXTR

Oxytocin receptor

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Tissue enriched

Purinergic receptor P2Y, G-protein coupled, 12

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

Purinergic receptor P2Y, G-protein coupled, 2

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Prostaglandin E receptor 1 (subtype EP1), 42kDa

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

Prostaglandin E receptor 2 (subtype EP2), 53kDa

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Prostaglandin E receptor 3 (subtype EP3)

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Prostaglandin E receptor 4 (subtype EP4)

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Expressed in all

Prostaglandin F receptor (FP)

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Prostaglandin I2 (prostacyclin) receptor (IP)

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Tissue enhanced

Parathyroid hormone 2 receptor

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Sphingosine-1-phosphate receptor 5

FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Tissue enhanced

SCTR

Secretin receptor

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

SMO

Smoothened, frizzled class receptor

Cancer-related genes
FDA approved drug targets
G-protein coupled receptors
Plasma proteins
Predicted membrane proteins

SPECC1L-ADORA2A

SPECC1L-ADORA2A readthrough (NMD candidate)

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

Somatostatin receptor 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Somatostatin receptor 2

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Somatostatin receptor 5

FDA approved drug targets
G-protein coupled receptors
Plasma proteins
Predicted membrane proteins

Plasma membrane

Tissue enhanced

Trace amine associated receptor 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tachykinin receptor 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Thromboxane A2 receptor

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Nuclear speckles
Plasma membrane

TSHR

Thyroid stimulating hormone receptor

Cancer-related genes
Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Predicted secreted proteins

Tissue enriched

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.